10/25/2026
Beekeepers have been losing a slow arms race against a mite for decades. The newest treatment works through a different route entirely.
Here’s the history. Varroa destructor jumped from Asian honeybees to Western honeybees in the twentieth century and reached the US in 1987. The Asian bees had evolved defenses over a very long time. Western bees hadn’t. The mite now lives in almost every hive in the country. It feeds on developing bees inside capped cells, and it spreads viruses like deformed wing virus, which leaves young bees with crumpled, useless wings.
The first big chemical answer was fluvalinate, sold as Apistan. It worked well, until mites evolved resistance. Coumaphos came next, and resistance followed again. Amitraz, sold as Apivar, became the go-to, and now some beekeepers report it failing too. Each time, the mites changed a little and survived the chemical.
That’s the core problem: when every treatment attacks mites the same way, they evolve their way around it.
Norroa, from GreenLight Biosciences, uses a different mechanism. Its active ingredient, vadescana, is a strand of double-stranded RNA matched to a gene varroa needs to reproduce. Bees eat it, and mites pick it up while feeding on the bees. Inside the mite, the RNA triggers the mite’s own gene-silencing machinery to shut down that reproduction gene. Mites stop making new mites, and the population declines. EPA classifies it as a new mode-of-action group, IRAC Group 35.
GreenLight says control lasts up to 18 weeks, the RNA breaks down quickly in the environment, and it can be used at any temperature as long as it’s safe to open the hive.
The real value is rotation. Using Norroa alongside other treatments, rather than in place of everything else, could help slow resistance on all of them.
The basics still matter, though. Test mite loads with an alcohol wash or sugar roll before you treat, and test again afterward.
Count first. Rotate treatments. Outsmart mites.